Baiyun has been committed to the development of the Guangdong-Hong Kong-Macao Greater Bay Area and emphasized on the construction of Guangzhou Private Science and Technology Park, Baiyun Lake Digital Technology City and Modern Urban Agriculture Demonstration Zone. It will strive to spur new vitality and develop itself into a central urban area with a focus on comprehensive urban functions, integrated cultural strength, the modern service industry and a modern and international business environment.

In 2025, the district's gross domestic product reached 331.2 billion yuan ($48 billion), ranking fourth in Guangzhou city. Its fixed-asset investment surpassed 100 billion yuan for six consecutive years, ranking second citywide. Total retail sales of consumer goods and total import and export value have both exceeded 100 billion yuan.

The district also ranked second in the city in total market entities.